cortisol

/kawr"teuh sawl', -sohl'/, n.
1. Biochem. one of several steroid hormones produced by the adrenal cortex and resembling cortisone in its action.
2. Pharm. hydrocortisone.
[1950-55; CORTIS(ONE) + -OL1]

* * *

also called  hydrocortisone 
 an organic compound belonging to the steroid family, the principal hormone secreted by the adrenal glands (adrenal gland). It is a potent anti-inflammatory agent and is also used for the palliative treatment of rheumatoid arthritis.

      In the blood the amounts of cortisol and corticosterone, another adrenal hormone, are monitored by the hypothalamus, a regulatory organ located at the forebrain. Low levels of these substances induce secretion of a releasing hormone, CRF (corticotropin-releasing factor), which acts upon the anterior pituitary, causing the release of ACTH ( adrenocorticotropic hormone). ACTH controls the secretion of cortisol from the adrenal cortex. High cortisol levels inhibit CRF-induced ACTH release. Cortisol is rapidly metabolized to several products that are excreted in the urine.

      Use of cortisol in therapy produces the same undesirable side effects as cortisone. Both drugs have been largely superseded by such synthetic steroids as prednisolone.

* * *


Universalium. 2010.

Look at other dictionaries:

  • Cortisol — Nombre (IUPAC) sistemático …   Wikipedia Español

  • Cortisol — Représentation moléculaire du Cortisol Général …   Wikipédia en Français

  • cortisol — ● cortisol nom masculin Hormone élaborée à partir du cholestérol, sécrétée par la glande corticosurrénale. cortisol n. m. BIOCHIM Hormone (17 hydroxycorticostérone) la plus active et la plus importante parmi les corticoïdes agissant sur le… …   Encyclopédie Universelle

  • cortisol — n. a steroid hormone ({C21H30O5}) active in carbohydrate and protein metabolism; called also {hydrocortisone}. It is used in medicine as an antiinflammatory agent Syn: hydrocortisone. [WordNet 1.5] …   The Collaborative International Dictionary of English

  • cortisol — Hormona esteroidea que existe de forma natural en el cuerpo y que se fabrica sintéticamente para uso farmacológico. Se emplea como agente antiinflamatorio. Diccionario Mosby Medicina, Enfermería y Ciencias de la Salud, Ediciones Hancourt, S.A.… …   Diccionario médico

  • Cortisol — Cortisol, zu den ⇒ Glucocorticoiden gehörendes Steroidhormon …   Deutsch wörterbuch der biologie

  • Cortisol — vgl. Kortisol. Cortison vgl. Kortison …   Das Wörterbuch medizinischer Fachausdrücke

  • cortisol — hydrocortisone, 1953, from CORTISONE (Cf. cortisone) + ol …   Etymology dictionary

  • cortisol — [kôrt′ə sôl΄, kôrt′əsōl΄] n. [ CORTISONE + OL1] HYDROCORTISONE …   English World dictionary

  • Cortisol — Not to be confused with cortisone, a similar compound with a similar name, genesis, and function. Cortisol Systematic (IUPAC …   Wikipedia

  • Cortisol — Strukturformel Allgemeines Freiname Hydrocortison Andere Namen …   Deutsch Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.