/klawr"euh kwin, -kween', klohr"-/, n. Pharm.
a synthetic substance, C18H26ClN3, used chiefly to control malaria attacks.
[1945-50; CHLORO-2 + QUIN(OLIN)E]

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      synthetic drug used in the treatment of malaria. Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate. It also can be given by intramuscular injection as chloroquine hydrochloride. Chloroquine is effective against susceptible strains of the malarial parasites Plasmodium vivax, P. ovale, and P. falciparum, as well as certain parasitic worms and amoebas (amoeba). Some mild side effects may occur, including headache and abdominal cramps, which are common to antimalarials. Visual impairment may occur with long-term use of chloroquine.

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Universalium. 2010.

Look at other dictionaries:

  • Chloroquine — Systematic (IUPAC) name N (7 chloroquinolin 4 yl) N,N diethyl pentane 1,4 diamine Clinical data Trade names …   Wikipedia

  • Chloroquine — Général Nom IUPAC N (7 chloroquinolin 4 yl) N,N diethyl pentane 1,4 diamine …   Wikipédia en Français

  • chloroquine — [ klɔrɔkin ] n. f. • 1953; en angl. 1946; de chloro et quin(oléine) ♦ Méd. Médicament synthétique employé dans le traitement du paludisme et de certaines arthrites. Syn. (déposé) NIVAQUINEn. f. ● chloroquine nom féminin Dérivé chloré de la… …   Encyclopédie Universelle

  • chloroquine — [klôr′ə kwin] n. [< CHLORO + QUIN(OLIN)E] a synthetic drug, C18H26ClN3, used in treating malaria, certain kinds of arthritis, etc …   English World dictionary

  • chloroquine — noun Etymology: chlor + quinoline Date: 1946 an antimalarial drug C18H26ClN3 administered in the form of its bitter crystalline diphosphate …   New Collegiate Dictionary

  • chloroquine — Antimalarial drug that has the interesting property of increasing the pH within the lysosomewhen added to intact cells in culture …   Dictionary of molecular biology

  • chloroquine — noun A 4 aminoquinoline drug used to treat and prevent malaria, having the chemical formula CHClN …   Wiktionary

  • chloroquine — An antimalarial agent used for the treatment and suppression of Plasmodium vivax, P. malariae, and P. falciparum; available as the phosphate and sulfate. It does not produce a radical cure because it has no effect on the exoerythrocytic stages; c …   Medical dictionary

  • chloroquine — [ klɔ:rə(ʊ)kwi:n, klɒ ] noun Medicine a synthetic drug related to quinoline, chiefly used against malaria …   English new terms dictionary

  • chloroquine — chlo·ro·quine …   English syllables

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