suramin

drug
      synthetic drug used in the treatment of sleeping sickness (African trypanosomiasis), a disease caused by an infestation of the protozoan Trypanosoma and spread by the tsetse fly. Suramin is administered by intravenous injection. It is most effective when given in the early stages of disease because it attacks the parasites as they circulate in the bloodstream and concentrate in the lymph nodes. (At a later stage they invade the spinal fluid.) Suramin has also been used in the treatment of river blindness ( onchocerciasis), a disease caused by the helminth Onchocerca volvulus and spread by the black fly Simulium.

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Universalium. 2010.

Look at other dictionaries:

  • Suramin — Systematic (IUPAC) name 8 [(4 methyl 3 {[3 ({[3 ({2 methyl 5 …   Wikipedia

  • Suramin — Suramin®   [Kurzwort] das, s, Germanin …   Universal-Lexikon

  • suramin — suràmīn m <G suramína> DEFINICIJA farm. lijek koji se upotrebljava za liječenje tripanosomijaze (kao i u tretiranju AIDS a) ETIMOLOGIJA fr. sur: nad + v. amin …   Hrvatski jezični portal

  • Suramin — Strukturformel Allgemeines Freiname Suramin Andere Namen …   Deutsch Wikipedia

  • suramin — sur·a·min su̇r ə mən n a trypanocidal drug C51H34N6Na6O23S6 obtained as a white powder and administered intravenously in the early stages of African sleeping sickness called also germanin, suramin sodium * * * n. a nonmetallic drug used in the… …   Medical dictionary

  • suramin — ˈsu̇rəmə̇n noun or suramin sodium ( s) Etymology: probably from surra + am + in : a trypanocidal drug C51H34N6Na6O23S6 obtained as a white powder and administered intravenously in the early stages of African sleeping sickness …   Useful english dictionary

  • suramin — Compound that uncouples G proteins from receptors, inhibits phospholipase D and inhibits binding of EGF, PDGF to cell surface receptors …   Dictionary of molecular biology

  • suramin — noun A drug used to treat onchocerciasis and human sleeping sickness caused by trypanosomes …   Wiktionary

  • Suramin — Su|ra|min * das; s Kunstw.; vgl. ↑...in> Mittel zur Behandlung der Schlafkrankheit …   Das große Fremdwörterbuch

  • suramin — sur·a·min …   English syllables

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