renal osteodystrophy

also called  renal rickets 

      chronic, probably hereditary disorder characterized by kidney dysfunction, bone-mineral loss and rickets-type deformities, calcifications in abnormal places, and overactivity of the parathyroid glands. Loss of calcium and retention of phosphorus occur because of the malfunctioning kidneys; this induces an overproduction of parathormone, which results in the demineralization of well-formed bones (bone disease) and an inability to calcify newly developing bone. The bone abnormalities develop more slowly than kidney insufficiency; if the latter is severe, death may occur in childhood before the skeletal abnormalities become apparent. If the kidney insufficiency is not total, it may cause dwarfing and frequent fractures in children; adults experience gradual softening and bowing of bones. Secondary hyperparathyroidism, a type of renal osteodystrophy, may be an acquired disease found in individuals with chronic renal failure. Although the effect of acquired disease on bone metabolism is more limited than that of hereditary renal osteodystrophy, because of its onset late in life, it causes similar changes in calcium and phosphorus metabolism and bone demineralization over time.

      Treatment of renal osteodystrophy depends on the state of chemical balance of the patient. Kidney transplant has been successful in some cases involving severe kidney dysfunction, and removal of the malfunctioning parathyroids is sometimes effective in controlling symptoms.

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Universalium. 2010.

Look at other dictionaries:

  • Renal osteodystrophy — Infobox Disease Name = Renal osteodystrophy Caption = DiseasesDB = ICD10 = ICD10|N|25|0|n|25 ICD9 = ICD9|588.0 ICDO = OMIM = MedlinePlus = eMedicineSubj = radio eMedicineTopic = 500 MeshID = D012080 Renal osteodystrophy is a bone pathology,… …   Wikipedia

  • Renal osteodystrophy — A combination of bone disorders usually caused by chronic kidney failure (renal disease). Can also occur because of abnormal kidney functioning at birth (congenital). When the kidneys have failed, death is imminent unless dialysis is given.… …   Medical dictionary

  • Osteodystrophy — Classification and external resources ICD 10 Q78.9 ICD 9 756.50 …   Wikipedia

  • renal rickets — n RENAL OSTEODYSTROPHY * * * rickets occurring in children and secondary to renal dysfunction asociated with hyperphosphatemia; the term is also used more loosely as a synonym of renal osteodystrophy …   Medical dictionary

  • Renal failure — Classification and external resources ICD 10 N17 N19 ICD 9 …   Wikipedia

  • osteodystrophy — Defective formation of bone. SYN: osteodystrophia. [osteo + G. dys, difficult, imperfect, + trophe, nourishment] Albright hereditary o. an inherited form of hyperparathyroidism associated with ectopic …   Medical dictionary

  • osteodystrophy — n. any generalized bone disease resulting from a metabolic disorder. In renal osteodystrophy chronic kidney failure leads to diffuse bone changes resulting from osteomalacia, secondary hyperparathyroidism (excessive secretion of parathyroid… …   The new mediacal dictionary

  • renal dwarfism — dwarfism resulting from chronic renal failure such as that of renal osteodystrophy …   Medical dictionary

  • Osteodystrophy, renal — A bone growth disorder caused by chronic kidney failure (renal disease). Also …   Medical dictionary

  • osteodystrophy — noun defective bone development; usually attributable to renal disease or to disturbances in calcium and phosphorus metabolism • Hypernyms: ↑dystrophy …   Useful english dictionary

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