severe brain damage caused by an abnormal concentration of the bile pigment bilirubin in brain tissues at or shortly after birth. Kernicterus may occur because of Rh blood-group (Rh blood group system) incompatibility between mother and child, as in erythroblastosis fetalis, where the mother's immune system destroys fetal blood cells, resulting in severe anemia and jaundice in the newborn. Other causes are certain types of drug therapy, cerebral palsy, and jaundice associated with prematurity. Symptoms of kernicterus include loss of the startle reflex, poor feeding, decreased movement, and seizures. If the infant survives, later effects of kernicterus may include movement disorders, hearing loss, and decreased mental ability. Transfusion therapy and phototherapy have greatly reduced the incidence of kernicterus.

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Universalium. 2010.

Look at other dictionaries:

  • kernicterus — impregnación bilirrubínica de la sustancia de los núcleos grises del cerebro y médula con degeneración de las células nerviosas. Es una forma grave de ictericia del recién nacido [ICD 10: P57.9] Diccionario ilustrado de Términos Médicos.. Alvaro… …   Diccionario médico

  • Kernicterus — ICDO = OMIM = MedlinePlus = 003243 eMedicineSubj = ped eMedicineTopic = 1247 MeshID = D007647 Kernicterus is damage to the brain centers of infants caused by increased levels of unconjugated indirect bilirubin which is free (not bound to albumin) …   Wikipedia

  • Kernicterus — Disorder due to jaundice in a newborn baby with a high blood level of the pigment bilirubin that is deposited in the brain resulting in damage. Some babies are at high risk. A baby who has bruises at birth is more likely to develop jaundice. A… …   Medical dictionary

  • Kernicterus — El kernicterus, ictericia nuclear o encefalopatía neonatal bilirrubínica es una complicación neurológica grave causada por la elevación de los niveles normales de bilirrubina en la sangre del neonato. Se debe a la acción directa de la bilirrubina …   Wikipedia Español

  • kernicterus — noun Damage to the brain centres of infants caused by increased levels of unconjugated indirect bilirubin which is free (not bound to albumin) …   Wiktionary

  • kernicterus — ker·nic·ter·us …   English syllables

  • kernicterus — n. staining and subsequent damage of the brain by bile pigment (bilirubin), which may occur in severe cases of haemolytic disease of the newborn. Immature brain cells in the basal ganglia are affected, and as brain development proceeds a pattern… …   The new mediacal dictionary

  • kernicterus — /kəˈnɪktərəs/ (say kuh niktuhruhs) noun a severe form of jaundice in the newborn, usually causing death or permanent brain damage. {German, from Kern core (see kern2) + Icterus icterus} …   Australian English dictionary

  • kernicterus — noun an abnormal accumulation of bile pigment in the brain and other nerve tissue; causes yellow staining and tissue damage • Hypernyms: ↑jaundice, ↑icterus …   Useful english dictionary

  • biliary encephalopathy — kernicterus …   Medical dictionary

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