Buck, Linda B.

▪ American physician
born January 29, 1947, Seattle, Washington, U.S.

      American scientist and corecipient, with Richard Axel (Axel, Richard), of the Nobel Prize for Physiology or Medicine in 2004 for discoveries concerning the olfactory system.

      Buck received a B.S. (1975) in both microbiology and psychology from the University of Washington and a Ph.D. (1980) in immunology from the University of Texas Southwestern Medical Center. She first worked with Axel in the early 1980s at Columbia University in New York City, where Axel was a professor and Buck was his postdoctoral student. Buck held various positions with the Howard Hughes Medical Institute (Hughes Medical Institute) (HHMI) and at Harvard Medical School from 1984 until 2002, when she joined the Fred Hutchinson Cancer Research Center in Seattle.

      In 1991 Buck and Axel jointly published a landmark scientific paper, based on research they had conducted with laboratory rats, that detailed their discovery of the family of 1,000 genes that encode, or produce, an equivalent number of olfactory receptors (olfactory receptor). These receptors are proteins responsible for detecting the odorant molecules in the air and are located on olfactory receptor cells, which are clustered within a small area in the back of the nasal cavity. The two scientists then clarified how the olfactory system functions by showing that each receptor cell has only one type of odour receptor, which is specialized to recognize a few odours. After odorant molecules bind to receptors, the receptor cells send electrical signals to the olfactory bulb in the brain. The brain combines information from several types of receptors in specific patterns, which are experienced as distinct odours.

      Axel and Buck later determined that most of the details they uncovered about the sense of smell are virtually identical in rats, humans, and other animals, although they discovered that humans have only about 350 types of working olfactory receptors, about one-third the number in rats. Nevertheless, the genes that encode olfactory receptors in humans account for about 3 percent of all human genes. The work helped boost scientific interest in the possible existence of human pheromones (pheromone), odorant molecules known to trigger sexual activity and certain other behaviour in many animals, and Buck's HHMI laboratory carried on research into how odour perceptions are translated into emotional responses and instinctive behaviour.

* * *

Universalium. 2010.

Look at other dictionaries:

  • Linda B. Buck — Saltar a navegación, búsqueda Linda B. Buck Linda B. Buck, médico, (nacida el 29 de enero, 1947) es una científica estadounidense conocida por sus trabajos sobre sistema olfatorio. Obtuvo junto a …   Wikipedia Español

  • Linda Buck — George W. Bush trifft sechs Nobelpreisträger von 2004. Linda B. Buck steht ganz links. Linda B. Buck (* 29. Januar 1947 in Seattle, Washington) ist eine US amerikanische Neurophysiologin. Für die Erforschung des …   Deutsch Wikipedia

  • Linda B. Buck — George W. Bush t …   Deutsch Wikipedia

  • Linda Buck — Linda B. Buck Pour les articles homonymes, voir Buck. Le Dr Linda B. Buck (29 Janvier 1947 à Seattle, État de Washington ) est une biologiste américaine, médaillée du Prix Nobel de médecine en 2004 et membre de la National Academy of Sciences… …   Wikipédia en Français

  • Buck — bezeichnet: Buck, im amerikanischen Englisch einen Slang Ausdruck für Dollar Buck, in südafrikanischem Englisch einen Slang Ausdruck für Südafrikanischer Rand Buck Converter in der Elektronik ein österreichisches süddeutsches Adelsgeschlecht,… …   Deutsch Wikipedia

  • Linda Buck — Linda Bruck Nombre Linda Bruck …   Wikipedia Español

  • Linda Shearman — Nation Vereinigtes Konigreich  Vereinigtes Königreich …   Deutsch Wikipedia

  • Linda Thorson — Données clés Nom de naissance Linda Robinson Naissance 18 juin 1947 Toronto, Ontario, Canada Nationalité …   Wikipédia en Français

  • Linda B. Buck — Linda B. Buck, médico, (nacida el 19 de enero, 1947) es una científica estadounidense conocida por sus trabajos sobre sistema olfatorio. Obtuvo junto a Richard Axel el Premio Nobel de Fisiología o Medicina de 2004 por sus trabajos sobre los… …   Enciclopedia Universal

  • Linda B. Buck — Infobox Scientist name = Linda B. Buck box width = image width = caption = birth date = birth date and age|1947|01|29 birth place = Seattle, Washington death date = death place = residence = citizenship = nationality = American ethnicity = field …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.