Ignarro, Louis J(oseph)

born May 31, 1941, Brooklyn, N.Y., U.S.

U.S. pharmacologist.

He earned a Ph.D. from the University of Minnesota. Along with Robert F. Furchgott and Ferid Murad, Ignarro was awarded a 1998 Nobel Prize for the discovery that nitric oxide acts as a signaling molecule in the cardiovascular system. Ignarro concluded that the factor that Furchgott had named endothelium-derived relaxing factor was nitric oxide. This work uncovered an entirely new mechanism by which blood vessels in the body relax and widen. It was the first discovery that a gas could act as a signaling molecule in a living organism. The principle behind the drug Viagra, used to treat impotence, was based upon this research.

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Universalium. 2010.

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  • Ignarro, Louis J(oseph) — (n. 31 may. 1941, Brooklyn, N.Y., EE.UU.). Farmacólogo estadounidense. Obtuvo un Ph.D. en la Universidad de Minnesota. En 1998 compartió el Premio Nobel con Robert F. Furchgott y Ferid Murad, por descubrir que el óxido nítrico actúa como molécula …   Enciclopedia Universal

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