Arber, Werner

born June 3, 1929, Gränichen, Switz.

Swiss microbiologist.

He has taught chiefly at the University of Basel. He shared a 1978 Nobel Prize with Daniel Nathans and Hamilton O. Smith for the discovery and use of restriction enzymes that break the giant molecules of DNA into pieces small enough to be separated for individual study but large enough to retain meaningful amounts of the genetic information of the original substance. He also observed that bacteriophages cause mutation in their bacterial hosts and undergo hereditary mutations themselves.

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▪ Swiss microbiologist
born June 3, 1929, Gränichen, Switz.

      Swiss microbiologist, corecipient (Smith, Hamilton Othanel) with (Nathans, Daniel) Daniel Nathans (Nathans, Daniel) and Hamilton Othanel Smith (Smith, Hamilton Othanel) (qq.v.) of the United States of the Nobel Prize for Physiology or Medicine for 1978. All three were cited for their work in molecular genetics, specifically the discovery and application of enzymes (restriction enzyme) that break the giant molecules of deoxyribonucleic acid (DNA) (DNA) into manageable pieces, small enough to be separated for individual study but large enough to retain bits of the genetic information inherent in the sequence of units that make up the original substance.

      Arber studied at the Swiss Federal Institute of Technology in Zürich, the University of Geneva, and the University of Southern California. He served on the faculty at Geneva from 1960 to 1970, when he became professor of microbiology at the University of Basel.

      During the late 1950s and early '60s Arber and several others extended the work of an earlier Nobel laureate, Salvador Luria (Luria, Salvador), who had observed that bacteriophages (bacteriophage) (viruses that infect bacteria) not only induce hereditary mutations in their bacterial hosts but at the same time undergo hereditary mutations themselves. Arber's research was concentrated on the action of protective enzymes present in the bacteria, which modify the DNA of the infecting virus—e.g., the restriction enzyme, so-called for its ability to restrict the growth of the bacteriophage by cutting the molecule of its DNA to pieces.

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Universalium. 2010.

Look at other dictionaries:

  • Arber , Werner — (1929–) Swiss microbiologist Arber, who was born in Gränichen, Switzerland, graduated from the Swiss Federal Institute of Technology in 1953 and gained his PhD from the University of Geneva in 1958. He spent a year at the University of Southern… …   Scientists

  • Arber,Werner — Ar·ber (ärʹbər), Werner. Born 1929. Swiss microbiologist. He shared a 1978 Nobel Prize for the discovery of restriction enzymes and their application to molecular genetics. * * * …   Universalium

  • Arber, Werner — ► (n. 1929) Microbiólogo suizo. Fue premio Nobel de Medicina y Fisiología en 1978, compartido con D. Nathans y H. O. Smith, por su labor investigadora sobre la ciencia del mecanismo genético. * * * (n. 3 jun. 1929, Gränichen, Suiza). Microbiólogo …   Enciclopedia Universal

  • Arber — Arber, Werner …   Enciclopedia Universal

  • Werner Arber — (2008) Werner Arber (* 3. Juni 1929 in Gränichen) ist ein Schweizer Mikrobiologe und Genetiker. 1978 erhielt er den Nobelpreis für Physiologie oder Medizin. Inhaltsverzeichnis …   Deutsch Wikipedia

  • ARBER (W.) — ARBER WERNER (1929 ) Né en Suisse, Werner Arber y a fait une carrière universitaire jusqu’en 1958. Chercheur à l’université de Los Angeles pendant deux ans, il devait rentrer dans son pays en 1960 pour y enseigner la génétique moléculaire et la… …   Encyclopédie Universelle

  • Werner — Werner, Abraham Gottlob Werner, Alfred Werner, Pierre Werner, Theodor Werner, Zacharias * * * (as used in expressions) Alexanderson, Ernst F(rederik) W(erner) Arber, Werner Bischof, Werner …   Enciclopedia Universal

  • Werner — /werr neuhr/; for 1 also Ger. /verdd neuhrdd/, n. 1. Alfred /al fred, frid/; Ger. /ahl frddayt/, 1866 1919, Swiss chemist: Nobel prize 1913. 2. a male given name. * * * (as used in expressions) Alexanderson Ernst Frederik Werner Arber Werner… …   Universalium

  • Werner Arber — en 2008. Werner Arber est un microbiologiste et un généticien suisse né le 3 juin 1929 à Gränichen en Argovie. Il a obtenu en 1978 le Prix Nobel de médecine avec Hamilton Smith et Daniel Nathans pour la découverte de l …   Wikipédia en Français

  • Werner Arber — en Roma en 2008. Nacimiento …   Wikipedia Español

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