therapeutic index

the ratio between the dosage of a drug that causes a lethal effect and the dosage that causes a therapeutic effect. Also called margin of safety.
[1925-30]

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Universalium. 2010.

Look at other dictionaries:

  • therapeutic index — n a measure of the relative desirability of a drug for the attaining of a particular medical end that is usu. expressed as the ratio of the largest dose producing no toxic symptoms to the smallest dose routinely producing cures * * * the ratio of …   Medical dictionary

  • Therapeutic index — The therapeutic index (also known as therapeutic ratio), is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxic effects. Quantitatively, it is the ratio given by the toxic dose… …   Wikipedia

  • therapeutic index — noun : a measure of the relative desirability of a drug for attaining a particular medical end that is usually expressed as the ratio of the largest dose producing no toxic symptoms to the smallest dose routinely producing cures * * * Pharm. the… …   Useful english dictionary

  • therapeutic index — the ratio of a dose of a therapeutic agent that produces damage to normal cells to the dose that is necessary to have a defined level of anticancer activity. It indicates the relative efficacy of a treatment against tumours …   The new mediacal dictionary

  • therapeutic index — ther′apeu′tic in′dex n. pha the ratio between the dosage of a drug that causes a lethal effect and the dosage that causes a therapeutic effect • Etymology: 1925–30 …   From formal English to slang

  • therapeutic index — noun Date: 1926 a measure of the relative desirability of a drug for the attaining of a particular medical end that is usually expressed as the ratio of the largest dose producing no toxic symptoms to the smallest dose routinely producing cures …   New Collegiate Dictionary

  • Индекс Терапевтический (Therapeutic Index) — соотношение между дозировкой лекарственного вещества, которая вызывает повреждение здоровых клеток, и дозировкой, которая необходима для достижения определенного уровня противоопухолевого действия данного вещества. Это соотношение отражает… …   Медицинские термины

  • Therapeutic window — (or pharmaceutical window) is an index for estimation of drug dosage which can treat disease effectively while staying within the safety range. In other words, it is the dosage of a medication between the amount that gives an effect (effective… …   Wikipedia

  • therapeutic window — n 1) the range of dosage of a drug or of its concentration in a bodily system that provides safe effective therapy <the narrow therapeutic window...the effect may go from therapeutic to toxic with an increase of just 10 micrograms per… …   Medical dictionary

  • therapeutic — index curative, cure, medicinal, palliative (abating), remedial, salubrious, salutary Burton s Legal Th …   Law dictionary

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