pantothenic acid

/pan"teuh then"ik, pan'-/, Biochem.
a hydroxy acid, C9H17O5N, found in plant and animal tissues, rice, bran, etc., that is part of the B complex of vitamins and is essential for cell growth.
[1930-35; < Gk pántothen from all quarters (panto- PANTO- + -then suffix of motion from) + -IC]

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Organic compound, essential in animal metabolism.

The nature of the bound form was clarified through the discovery and synthesis (1947–50) of the compound pantetheine, which contains pantothenic acid combined with the compound thioethanolamine. Pantetheine is part of two larger compounds (coenzyme A and acyl-carrier protein) that promote a large number of metabolic reactions essential for the growth and well-being of animals. A dietary deficiency severe enough to lead to clear-cut disease has not been described in humans; however, when a person is severely malnourished, deficiency of the vitamin appears to contribute to the observed weakness and mental depression.

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      water-soluble vitamin essential in animal metabolism. Pantothenic acid, a growth-promoting substance for yeast and certain bacteria, appears to be synthesized by bacteria in the intestines of the higher animals. It was first isolated from liver cells in 1938 and was first synthesized in 1940. It has the following chemical structure:

      The vitamin is widespread in nature—especially in yeasts, liver, kidney, eggs, whole grains, and legumes—though it does not exist in its free form in animal tissue. The nature of the bound form was clarified through the discovery and synthesis (1947–50) of the compound pantetheine, which contains pantothenic acid combined with the compound thioethanolamine. Pantetheine is part of two larger compounds (coenzyme A and acyl-carrier protein) that promote a large number of metabolic reactions essential for the growth and well-being of animals. In the absence of pantothenic acid, experimental animals fail to grow, develop skin lesions, and frequently show a graying of the hair. A dietary deficiency severe enough to lead to clear-cut disease has not been described in humans; however, when a person is severely malnourished, deficiency of the vitamin appears to contribute to the observed weakness and mental depression.

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Universalium. 2010.

Look at other dictionaries:

  • Pantothenic acid — is vitamin B5, one of the less well known B vitamins, perhaps because it is widely distributed in nature. Pantothenic acid is virtually ubiquitous. It is present in foods as diverse as poultry, soybeans, yogurt, and sweet potatoes. No naturally… …   Medical dictionary

  • pantothenic acid — pantothenic acid. См. витамин В5. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • pantothenic acid — [pan΄tō then′ik] n. [Gr pantothen, from every side < pantos (see PANTO ) + IC] a yellow, viscous oil, C9H17NO5, a member of the vitamin B complex, widely distributed in animal and plant tissues and prepared synthetically: thought to be… …   English World dictionary

  • Pantothenic acid — Chembox new ImageFile=Pantothenic acid structure.svg ImageSize=300px IUPACName=3 [(2,4 dihydroxy 3, 3 dimethyl 1 oxobutyl) amino] propanoic acid OtherNames= Section1= Chembox Identifiers CASNo=137 08 6 PubChem=988… …   Wikipedia

  • pantothenic acid — a B vitamin that is a constituent of coenzyme A. It plays an important role in the transfer of acetyl groups in the body. Pantothenic acid is widely distributed in food and a deficiency is therefore unlikely to occur …   The new mediacal dictionary

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  • pantothenic acid — noun Etymology: Greek pantothen from all sides, from pant , pas all more at pan Date: 1933 a viscous oily acid C9H17NO5 of the vitamin B complex found in all living tissues …   New Collegiate Dictionary

  • pantothenic acid — pan′to•then′ic ac′id [[t]ˈpæn təˈθɛn ɪk, ˌpæn [/t]] n. biochem. nut a hydroxy acid, C9H17O5N, that is a component of the vitamin B complex, abundant in liver, yeast, and bran • Etymology: 1930–35; < Gk pántothen from all quarters (panto panto… …   From formal English to slang

  • pantothenic acid — /ˌpæntəθɛnɪk ˈæsəd/ (say .pantuhthenik asuhd) noun an oily hydroxy acid, HOCH2C(CH)2CHOHCONHCH2CH2COOH, found in plant and animal tissues, rice, bran, etc., which is essential for cell growth, and is a constituent of coenzyme A …   Australian English dictionary

  • pantothenic acid — a B vitamin essential in the diet of many cultured species …   Dictionary of ichthyology

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