/i mip"reuh meen'/, n. Pharm.
a tricyclic antidepressant, C19H24N2, used for the symptomatic relief of depression.
[1955-60; contr. and rearrangement of iminodibenzyl and aminopropyl, components of the chemical name]

* * *

      synthetic drug used in the treatment of depression and enuresis (bed-wetting). Introduced into medicine in the 1960s, imipramine was the first tricyclic antidepressant, a class named for its three-ring molecular structure. Imipramine inhibits reuptake of the neurotransmitters norepinephrine (epinephrine and norepinephrine) and serotonin in the brain. It is usually administered orally but may be given by intramuscular injection. The drug has a wide variety of side effects, which include dryness of the mouth, blurred vision, constipation, difficulty in passing urine, and cardiovascular abnormalities.

* * *

Universalium. 2010.

Look at other dictionaries:

  • Imipramine — Systematic (IUPAC) name 3 (10,11 dihydro 5H dibenzo[b,f]azepin 5 yl) N,N dimethylpropan 1 amine Clinical data Trade names …   Wikipedia

  • Imipramine — Schéma de l imipramine Général Nom IUPAC Imipramine …   Wikipédia en Français

  • imipramine — ● imipramine nom féminin Antidépresseur tricyclique du groupe des dibenzoazépines, utilisé dans les dépressions sévères et dans le traitement de certaines douleurs chroniques …   Encyclopédie Universelle

  • imipramine — [i mi′prə mēn΄] n. [ IMI(DE) + PR(OPYL) + AMINE] a white, crystalline powder, C19H24N2, used as an antidepressant …   English World dictionary

  • imipramine — noun Etymology: imide + propyl + amine Date: 1958 a tricyclic antidepressant drug C19H24N2 …   New Collegiate Dictionary

  • imipramine — noun a tricyclic heterocyclic compound used to treat depression …   Wiktionary

  • imipramine — imip·ra·mine im ip rə .mēn n a tricyclic antidepressant drug administered esp. in the form of its hydrochloride C19H24N2·HCl or pamoate (C19H24N2)2·C23H16O6 see TOFRANIL * * * n. a drug administered by mouth or injection to treat depression (see …   Medical dictionary

  • imipramine — [ɪ mɪprəmi:n] noun Medicine a synthetic compound used to treat depression. Origin 1950s: from imi(ne) + pr(opyl) + amine …   English new terms dictionary

  • imipramine — imip·ra·mine …   English syllables

  • imipramine — n. a drug administered by mouth or injection to treat depression (see antidepressant) and, in children, bedwetting. Its effects may be slow to develop; common side effects include dry mouth, blurred vision, constipation, sweating, and rapid… …   The new mediacal dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.