growth hormone

any substance that stimulates or controls the growth of an organism, esp. a species-specific hormone, as the human hormone somatotropin, secreted by the anterior pituitary gland. Abbr.: GH
[1920-25]

* * *

also called  somatotropin , or  human growth hormone 

      peptide hormone secreted by the anterior lobe of the pituitary gland. It stimulates growth of bone and essentially all tissues of the body by stimulating protein synthesis and breaking down fat to provide energy. GH stimulates the liver to produce somatomedins (secondary hormones) that have an insulin-like effect. The human somatomedin level rises progressively during childhood and reaches its peak during the growth spurt that occurs in puberty.

      GH deficiency is one of many causes of dwarfism. When treated over a period of years with human GH, affected children responded dramatically. For decades, however, availability of the hormone was limited, because it was obtained solely from human cadaver pituitaries. In 1985 use of natural GH was halted in the United States and several other countries because of the possibility that the hormone transmitted a fatal slow-virus disease known as Creutzfeldt-Jakob disease. That same year, by means of recombinant-DNA techniques, scientists were able to produce a biosynthetic human growth hormone they called somatrem, thus assuring a virtually unlimited supply of this once-precious substance.

* * *


Universalium. 2010.

Look at other dictionaries:

  • Growth hormone 2 — Growth hormone 2, also known as GH2, is a human gene.cite web | title = Entrez Gene: GH2 growth hormone 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=2689| accessdate = ] PBB Summary section title =… …   Wikipedia

  • Growth hormone 1 — Growth hormone 1, also known as GH1, is a human gene. PBB Summary section title = summary text = The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The… …   Wikipedia

  • growth hormone — n. 1. a polypeptide hormone of the anterior part of the pituitary gland, that promotes normal growth 2. any of various substances that promote growth, as of plants or beef cattle …   English World dictionary

  • growth hormone — ► NOUN ▪ a hormone which stimulates growth in animal or plant cells …   English terms dictionary

  • growth hormone — growth hormone. См. соматотропный гормон. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Growth hormone — HGH redirects here. For other uses, see HGH (disambiguation). Growth hormone 1 Growth hormone Identifiers Symbol GH1 …   Wikipedia

  • Growth hormone — A hormone made in the pituitary gland that stimulates the release of another hormone called somatomedin by the liver, thereby causing growth. Growth hormone is synonymous with somatotropin and somatropin. More specifically (and technically),… …   Medical dictionary

  • growth hormone — GH; = somatotrophin a hormone, synthesized and stored in the anterior pituitary gland, that promotes growth of the long bones in the limbs and increases protein synthesis (via somatomedin). Its release is controlled by the opposing actions of… …   The new mediacal dictionary

  • Growth Hormone — Somatotropin Strukturmodell des Somatotropin nach Kristallstruktur.[1] …   Deutsch Wikipedia

  • growth hormone — UK / US noun [countable] Word forms growth hormone : singular growth hormone plural growth hormones biology a hormone that helps the process of growth in animal and plant cells. In animals, it is produced in the pituitary gland …   English dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.