- Med.the application of genetic engineering to the transplantation of genes into human cells in order to cure a disease caused by a genetic defect, as a missing enzyme. Cf. gene transfer.[1970-75]
* * *or gene transfer therapyIntroduction of a normal gene into an individual in whom that gene is not functioning, either into those tissue cells that normally express the gene (curing that individual only) or into an early embryonic cell (curing the individual and all future offspring).Prerequisites for each procedure include finding the best delivery system (often a virus) for the gene, demonstrating that the transferred gene can express itself in the host cell, and establishing that the procedure is safe. Diseases for which gene-therapy research is advanced include cystic fibrosis, Huntington's disease, and familial hypercholesterolemia; research continues on its application for Alzheimer's disease, breast and other cancers, and diabetes. Some aspects of gene therapy, including genetic manipulation and selection, research on embryonic tissue, and experimentation on human subjects, have aroused ethical controversy.
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Gene therapy — using an Adenovirus vector. A new gene is inserted into an adenovirull. If the treatment is successful, the new gene will make a functional protein. Gene therapy is the insertion, alteration, or removal of genes within an individual s cells and… … Wikipedia
gene therapy — n the insertion of usu. genetically altered genes into cells esp. to replace defective genes in the treatment of genetic disorders or to provide a specialized disease fighting function (as the destruction of tumor cells) gene therapist n * * *… … Medical dictionary
gene therapy — gene therapy. См. генотерапия. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
gene therapy — gene .therapy n [U] a way of treating certain diseases by using ↑genetic engineering … Dictionary of contemporary English
gene therapy — gene ,therapy noun uncount a medical treatment in which genes are put into cells in the body in order to cure some types of illness … Usage of the words and phrases in modern English
gene therapy — ► NOUN ▪ the introduction of normal genes into cells in place of missing or defective ones in order to correct genetic disorders … English terms dictionary
gene therapy — n. the experimental treatment of a disease by the use of techniques associated with genetic engineering, as to modify or replace the disease causing genes of certain cells … English World dictionary
gene therapy — treatment directed to curing genetic disease by introducing normal genes into patients to overcome the effects of defective genes, using techniques of genetic engineering. The most radical approach would be to do this at a very early stage in the … The new mediacal dictionary
gene therapy — noun : the insertion of usually genetically altered genes into cells especially to replace defective genes in the treatment of genetic disorders or to provide a specialized disease fighting function (as the destruction of tumor cells) • gene… … Useful english dictionary
gene therapy — The proposed treatment of an inherited disease by the transformation of an affected individual with a wild type copy of the defective gene causing the disorder. In germ line (or heritable) gene therapy, reproductive cells are transformed; in… … Glossary of Biotechnology